IRIDOVIRUS CARD PROTEIN INHIBITS APOPTOSIS THROUGH INTRINSIC AND EXTRINSIC PATHWAYS.

Grouper iridovirus (GIV) belongs to the genus Ranavirus of the family Iridoviridae; the genomes of such viruses contain an anti-apoptotic caspase recruitment domain (CARD) gene.The GIV-CARD gene encodes a protein of 91 amino acids with a molecular mass of 10,505 Daltons, and shows high similarity to other viral CARD genes and human ICEBERG.In this

Abstract Background Gene duplication and subsequent functional divergence especially expression divergence have been widely considered as main sources for evolutionary innovations.Many studies evidenced that genetic regulatory network evolved rapidly shortly Spoons after gene duplication, thus leading to accelerated expression divergence and divers